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Arq. bras. oftalmol ; 78(3): 185-186, May-Jun/2015. tab, graf
Article in English | LILACS | ID: lil-753012

ABSTRACT

ABSTRACT Permanent visual loss can be caused by improper use of immunosuppressive therapy in cases of uveitis without differential diagnosis of syphilitic uveitis. We present four cases of syphilitic uveitis that were incorrectly diagnosed as being secondary to rheumatic diseases and were subsequently treated with immunosuppressive therapy, leading to permanent visual loss. These cases highlight the importance of ruling out syphilis in the differential diagnosis of inflammatory ocular diseases before starting use of immunosuppressive therapy.


RESUMO Elucidar os efeitos adversos do uso de medicações imunossupressoras em pacientes com uveíte não diagnosticada por sífilis. Avaliação de quatro pacientes com uveíte por sífilis submetidos a tratamento com drogas imunossupressoras por suspeita de uveíte secundária a doenças reumáticas, que desenvolveram perda visual permanente. Sífilis deve ser sempre um diagnóstico diferencial nas doenças inflamatórias oculares, principalmente antes do início de terapia imunossupressora.


Subject(s)
Female , Humans , Male , Middle Aged , Immunosuppressive Agents/adverse effects , Syphilis/drug therapy , Uveitis/drug therapy , Vision Disorders/etiology , Diagnosis, Differential , Fluorescent Treponemal Antibody-Absorption Test , Immunosuppressive Agents/therapeutic use , Syphilis/complications , Uveitis/etiology , Visual Acuity/drug effects
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